REVISTA ELETRÔNICA EXTENSÃO EM DEBATE

O PAPEL DO TNF-α NO DESENVOLVIMENTO DE DOENÇAS PSIQUIÁTRICAS

UMA REVISÃO SISTEMÁTICA

Carla Souza Anjos

Universidade Federal de Alagoas

https://orcid.org/0000-0002-8403-9943

Carla Eduarda Silva da Fonseca

Universidade Federal de Alagoas, campus Arapiraca

Letícia Henrique Leite da Silva

Universidade Federal de Alagoas, campus Arapiraca

Pedro Bezerra de Oliveira Neto

Acadêmico em Ciências Biológicas, Universidade Federal de Alagoas

Bruna Brandão dos Santos

Mestre em Ciências da Saúde, Instituto de Ciências Biológicas e da Saúde da Universidade Federal de Alagoas

Renise Bastos Farias Dias

Universidade Federal de Alagoas, campus Arapiraca

DOI: https://doi.org/10.28998/rexd.v14.15340

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Resumo

Este trabalho tem por objetivo realizar uma revisão sistemática da literatura sobre o papel do fator de necrose tumoral no desenvolvimento de doenças psiquiátricas. Foi realizada uma revisão sistemática da literatura realizada no SciELO, PubMed, Science Direct e MEDLINE. Os Descritores em Ciências da Saúde utilizados para as buscas foram: (TNF) (dependence) (“psychiatric disease or psychiatric disorders”). Foram totalizados 11 artigos para compor a amostra final deste estudo. Os estudos apontaram que as desordens psiquiátricas estão associadas a altas concentrações do fator de necrose tumoral, sendo moduladas a partir da exposição a substâncias inflamatórias, como por exemplo, o consumo de álcool e de outras drogas. Portanto, a literatura evidenciou que os níveis elevados de TNF-α possuem correlação significativa com transtornos mentais, sendo desencadeado pela produção de fatores exógenos, como o consumo de álcool.

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Biografia do Autor

Carla Souza Anjos, Universidade Federal de Alagoas

Acadêmica de Enfermagem pela Universidade Federal de Alagoas, campus Arapiraca. Bolsista pelo programa da PROEX com o projeto: "Intervenções em Saúde em usuários de substâncias psicoativas com ênfase em saúde mental: promovendo círculos comunitários".

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