REVISTA ELETRÔNICA EXTENSÃO EM DEBATE

O PAPEL DO TNF-α NO DESENVOLVIMENTO DE DOENÇAS PSIQUIÁTRICAS

UMA REVISÃO SISTEMÁTICA

Carla Souza Anjos

Universidade Federal de Alagoas

https://orcid.org/0000-0002-8403-9943

Carla Eduarda Silva da Fonseca

Universidade Federal de Alagoas, campus Arapiraca

Letícia Henrique Leite da Silva

Universidade Federal de Alagoas, campus Arapiraca

Pedro Bezerra de Oliveira Neto

Acadêmico em Ciências Biológicas, Universidade Federal de Alagoas

Bruna Brandão dos Santos

Mestre em Ciências da Saúde, Instituto de Ciências Biológicas e da Saúde da Universidade Federal de Alagoas

Renise Bastos Farias Dias

Universidade Federal de Alagoas, campus Arapiraca

DOI: https://doi.org/10.28998/rexd.v14.15340

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Abstract

This paper aims to perform a systematic review of the literature on the role of tumor necrosis factor in the development of psychiatric disorders. A systematic review of the literature was carried out in SciELO, PubMed, Science Direct and MEDLINE. The Health Science Descriptors used for the search were: (TNF) (dependence) ("psychiatric disease or psychiatric disorders"). A total of 11 articles made up the final sample for this study. The studies pointed out that psychiatric disorders are associated with high concentrations of tumor necrosis factor, being modulated from exposure to inflammatory substances, such as the consumption of alcohol and other drugs. Therefore, the literature showed that high levels of TNF-α have a significant correlation with mental disorders, being triggered by the production of exogenous factors, such as alcohol consumption.

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Author Biography

Carla Souza Anjos, Universidade Federal de Alagoas

Acadêmica de Enfermagem pela Universidade Federal de Alagoas, campus Arapiraca. Bolsista pelo programa da PROEX com o projeto: "Intervenções em Saúde em usuários de substâncias psicoativas com ênfase em saúde mental: promovendo círculos comunitários".

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